RNA Details
Disease Name
nephritis interstitia
Tissue
kidney
RNA Symbol
Hotair
RNA ID
RNA Type
lncrna
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
qRT-PCR;
Target
NOTCH1
Pathway
NA
PubMed ID
Title
LncRNA HOTAIR promotes renal interstitial fibrosis by regulating Notch1 pathway via the modulation of miR-124
Year
2019
Function
"Silencing lncrna hotair can up-regulate miR-124 to block notch2 pathway, and thereby alleviating epithelial-mesenchymal transition and renal interstitial fibrosis."